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The convergence of GLP-1 signaling with pathways of aginginsulin sensitivity, mitochondrial function, neuroinflammationsuggests these drugs may influence healthspan, not just body weight. (de Cabo & Mattson, 2019) For women entering their 50s and 60s, this convergence is especially powerful
RIPK3 blockade attenuates tubulointerstitial fibrosis in a mouse model of diabetic nephropathy
People taking Wegovy lost an average of about 15% of their body weight over 68 weeks
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